In 1942, at the height of British industrial war mobilization, an unlikely cohort scavenged the nation’s coastline for a precious substance. Among them were researchers, lighthouse keepers, members of the Royal Air Force and the Junior Red Cross, plant collectors from the County Herb Committee, Scouts and Sea Scouts, schoolteachers and students. They were looking for fronds and tufts of seaweed containing agar, a complex polysaccharide that forms the rigid cell walls of certain red algae.
Infigratinib靶向的FGFR3（成纤维细胞生长因子受体3）正是驱动ACH疾病发生的关键靶点，2月12日，BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果，公司计划下半年向FDA提交新药申请。
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